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Anti-heart failure treatment At the moment, there are a number of randomized controlled trials aimed at assessing the efficacy of pharmacological interventions, device-based therapies, or cardiac transplantation in -thalassemia patients with HF

78 These DAMPs play a major role in promoting neutrophil infiltration by activating antigen-presenting cells, including Kupffer cells and dendritic cells, which amplifies the immune response and the progression of liver injury

In the case of oxidative stress, JNK increases the phosphorylation of SARM1, resulting in enhanced NAD + degradation activity, which in turn promotes the suppression of mitochondrial respiration